Author: heejeongryu

Simultaneous profiling of 3D genome structure and DNA methylation in single human cells

Simultaneous profiling of 3D genome structure and DNA methylation in single human cells Dynamic three-dimensional chromatin conformation is a critical mechanism for gene regulation during development and disease. Despite this, profiling of three-dimensional genome structure from complex tissues with cell-type specific resolution remains challenging. Recent efforts...

Protein-based Intracellular Drug Delivery Platforms

Mining Metabolites from Microbiota

Targeting CaV3.1 gene for treating brain disorders

Next generation of protein structure analysis using ColabFold and Foldseek

Structure prediction with AlphaFold2 is set to have a huge impact on biology, medicine, and biotechnology. AlphaFold2 is not only accurate but, if optimized, also fast. Our ColabFold-AlphaFold2 pipeline accurately predicts the structures of a whole proteome within two days on a single GPU, approx....

Virus-assisted mapping of stress circuits

Histone sumoylation and chromatin dynamics

Human neural organoids for biomedical research

Optical microscopy for medical applications

Modulation of cytokine storm and tumorigenesis by innate immunity