SEMINAR  /  Biomedical Engineering

Suboptimal Paths in Medicine

We all behave: patients, clinicians, everyone. In most clinical practices, the states and conditions of clinical situations change sequentially. We can define a trajectory to characterize a patient’s health status. Clinicians strive to improve a patient’s health through timely interactions, which include ordering laboratory tests,...

SEMINAR  /  Biological Sciences

Decoding Exercise at Molecular Levels and Health

SEMINAR  /  Biomedical Engineering

3D Imaging and Optogenetic Pacing of in Vitro and in Vivo Model Systems

SEMINAR  /  Biological Sciences

Unravelling atopic dermatitis and psoriasis using single cell Rnaseq

Unravelling atopic dermatitis and psoriasis using single cell Rnaseq   Seunghee Hong Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea   Atopic dermatitis (AD) and psoriasis are prevalent chronic inflammatory skin diseases primarily mediated by T cells, often...

SEMINAR  /  Biomedical Engineering

Robust and scalable single-molecule protein sequencing with fluorosequencing

Abstract The need to accurately survey proteins and their modifications with ever higher sensitivities, particularly in clinical settings with limited samples, is spurring development of new single molecule proteomics technologies. Here, we describe our optimization of one such highly parallelized single molecule peptide sequencing platform,...

SEMINAR  /  Biomedical Engineering

Scalable single nucleus RNA sequencing of heavily-fixed or FFPE tissues by fixative exchange (FX)-seq

Scalable single nucleus RNA sequencing of heavily-fixed or FFPE tissues by fixative exchange (FX)-seq Chang Ho Sohn Yonsei University   Recent advances in single cell analyses by next-generation sequencing have broaden our understanding about how complex biological systems work at single cell level. Yet, current...

SEMINAR  /  Biological Sciences

Regulation of sleep homeostasis in distinct neuronal population by kinase signaling pathway