SEMINAR  /  Biological Sciences

Unravelling atopic dermatitis and psoriasis using single cell Rnaseq

Unravelling atopic dermatitis and psoriasis using single cell Rnaseq   Seunghee Hong Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea   Atopic dermatitis (AD) and psoriasis are prevalent chronic inflammatory skin diseases primarily mediated by T cells, often...

SEMINAR  /  Biomedical Engineering

Robust and scalable single-molecule protein sequencing with fluorosequencing

Abstract The need to accurately survey proteins and their modifications with ever higher sensitivities, particularly in clinical settings with limited samples, is spurring development of new single molecule proteomics technologies. Here, we describe our optimization of one such highly parallelized single molecule peptide sequencing platform,...

SEMINAR  /  Biomedical Engineering

Scalable single nucleus RNA sequencing of heavily-fixed or FFPE tissues by fixative exchange (FX)-seq

Scalable single nucleus RNA sequencing of heavily-fixed or FFPE tissues by fixative exchange (FX)-seq Chang Ho Sohn Yonsei University   Recent advances in single cell analyses by next-generation sequencing have broaden our understanding about how complex biological systems work at single cell level. Yet, current...

SEMINAR  /  Biological Sciences

Regulation of sleep homeostasis in distinct neuronal population by kinase signaling pathway

SEMINAR  /  Biological Sciences

How does integrin tension affect the onset of diseases?

SEMINAR  /  Biological Sciences

Role of PD-1 in regulatory T cells in tumor microenvironment

SEMINAR  /  Biomedical Engineering

Evidence for forward and reverse aging via epigenetic manipulation

Abstract Evidence for forward and reverse aging via epigenetic manipulation All living things experience entropy, manifested as a loss of inherited genetic and epigenetic information. In mammals, epigenetic information is also lost over time, but what causes it to be lost and whether it is...